research The role of the microenvironment on the fate of adult stem cells
The microenvironment controls adult stem cells' behavior and fate.
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research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hrrh-R) in the Hairless Gene (Hr)
A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model
Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
research Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury
Exosomes from modified stem cells may help treat liver injury.
research Heterogeneity of neural crest-derived melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data
Gene differences found in hair follicles linked to male baldness.
research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia
The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease
Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
research Tissue homeostasis
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Hair-growth as anti-aging
Anti-aging treatments like hair transplants, minoxidil, and finasteride effectively promote hair growth.
research Meta-Analysis of Gene Expression Reveals the Core Transcriptomic Profile of Lesional Scalp in Alopecia Areata
Alopecia areata involves specific gene changes and immune pathways, offering new treatment targets.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research 203 Rebalance of the scalp microbiota by a multifunctional ingredient
Dutasteride improved hair density and thickness in men not helped by finasteride, with minimal side effects.
research 201 Analysis of mice skin distribution using MALDI-MSI after subcutaneous injections of a new potent novel inhibitor of human hair growth, FOL-005
Some men don't respond to common hair loss treatments, but a new inhibitor, FOL-005, shows promise for targeting unwanted hair growth.
research Valentina Greco: Got hair?
Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
research Responses of type II spiral ganglion neurites to stripes of laminin and fibronectin
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
research 200 Uncommon finasteride side effects in male androgenic alopecia
research 198 Dutasteride for men with androgenic alopecia unresponsive to finasteride
research 199 Hand preference and sexual orientation as useful elements to predict finasteride side effects in male androgenic alopecia
research Epidermal Growth Factor Upregulates Production of Supernumerary Hair Cells in Neonatal Rat Organ of Corti Explants
Epidermal growth factor increases extra hair cells in newborn rat ears.
research Estrogens
research The Anti-atopic Lotions Containing Fucoidan Extracted from Ecklonia Cava Impact on Hairless Mice Atopic Dermatitis Skin
Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.
research ANALYSIS OF THE BACKGROUND LEVEL OF CYTOKINES M1 AND M2 OF THE MACROPHAGE PHENOTYPE IN PATIENTS WITH REVISION RHINOPLASTY AFTER THE USE OF THE DRUG PDRN
PDRN may reduce inflammation and complications in revision rhinoplasty for patients with high fibrinogen levels.
research Lectinhistochemistry of Dorsal Skin of Wistar-derived Hypotrichotic WBN/Ila-Ht Rats.
The skin of both rat strains showed similar lectin binding patterns.
research Human hair follicles are an extrarenal source and a nonhematopoietic target of erythropoietin
Human hair follicles produce and respond to erythropoietin, helping protect against stress.
research The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis
Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.