25 citations
,
January 2005 in “Pediatric Dermatology” Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
21 citations
,
January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
16 citations
,
January 2005 in “Pediatric Dermatology” A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.
14 citations
,
January 2005 in “Pediatric Dermatology” UVA1-light therapy successfully treated a child's skin condition, mycosis fungoides.
12 citations
,
January 2005 in “Pediatric Dermatology” Fox Fordyce disease might be more common in prepubertal girls than thought and can be managed with treatment.
11 citations
,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.
9 citations
,
January 2005 in “Pediatric Dermatology” Fox Fordyce disease can occur in prepubertal girls and may be underdiagnosed.
3 citations
,
February 2008 in “Basic and clinical dermatology” Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
2 citations
,
March 2019 in “Experimental Techniques in Urology & Nephrology” Heptaminol may cause hair lightening in hemodialysis patients.
February 2024 in “Planta” TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.
July 2020 in “International Journal of Dermatology Venereology and Leprosy Sciences” Most postmenopausal women experience skin and hair issues, so regular check-ups are important.
January 2005 in “Pediatric Dermatology” Alopecia areata in infants may be more common than previously thought.
370 citations
,
September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
175 citations
,
April 1982 in “Journal of The American Academy of Dermatology” Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
171 citations
,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
9 citations
,
September 2000 in “Obstetrics and gynecology clinics of North America” Hirsutism causes significant psychological distress in women.
GV-350 improves hair growth and quality of life in iron-deficient women without side effects.
40 citations
,
November 2009 in “Experimental Dermatology” The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
32 citations
,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
29 citations
,
June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.
22 citations
,
September 2004 in “Journal of The European Academy of Dermatology and Venereology” Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
May 2009 in “The American Journal of Dermatopathology” Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
137 citations
,
June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
April 2018 in “Journal of Investigative Dermatology” Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
1533 citations
,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
829 citations
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May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.