research Cellular and Immunological Aspects of Basel Cell Carcinoma
Basal cell carcinoma cases are rising globally.
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240-270 / 1000+ resultsresearch The Immunohistochemical Changes of Skin during Hair Follicle Cycle after Depilation in Mice
Hair growth after depilation increases skin thickness, mast cell counts, and cell activity.
research Multi‐tasking epidermal stem cells: Beyond epidermal maintenance
Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research Vitamin D receptor ablation alters skin architecture and homeostasis of dendritic epidermal T cells
Lack of Vitamin D receptor changes skin structure and increases certain immune cells in the skin.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
research A function for Rac1 in the terminal differentiation and pigmentation of hair
Rac1 is crucial for normal hair structure and pigmentation.
research Abstract 94: Hyaluronan Synthase 2 Knock Down in Epidermis Alter Wound Healing and Hair Follicle Development
Hyaluronan from Has2 is important for proper wound healing and hair follicle development.
research Decision letter: Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.
research Human epidermal neural crest stem cells as a source of Schwann cells
Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
research P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells
P63 is a marker for epidermal stem cells in rats.
research Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration
Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
research Hair growth inhibition by heparin in mice: a model system for studying the modulation of epithelial cell growth by glycosaminoglycans?
Heparin can inhibit hair growth in mice when injected.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research The hair cycle and Vitamin D receptor
Vitamin D receptor is essential for healthy hair growth.
research Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle
Sgk3 is essential for normal hair follicle growth and maintenance.
research Intralesional therapy for the treatment of keratoacanthoma
Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research IMMUNOPATHOLOGY OF THE HUMAN HAIR FOLLICLE
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research Artificial Pigmented Human Skin Created by Muse Cells
Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
research MG53 Mitigates Nitrogen Mustard-Induced Skin Injury
MG53 helps reduce skin damage caused by nitrogen mustard.
research Thymic epithelial cells : relatives of multipotent stem cells of the skin
Thymic epithelial cells may be related to skin stem cells.
research Investigating the roles of cellular senescence in embryogenesis and aging
Cellular senescence is crucial for normal embryonic development but contributes to aging in adults.
research Deficiency of Crif1 in hair follicle stem cells retards hair growth cycle in adult mice
Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
research Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening
The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
research Anatomy and Physiology of the Skin
The skin is essential for protection, temperature control, and immune defense.
research Multifunctional Merkel cells: Their roles in electromagnetic reception, finger-print formation, Reiki, epigenetic inheritance and hair form
Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.
research Epimorphin and Epithelial Morphogenesis
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.