409 citations
,
May 1991 in “Genes & Development” TGF-alpha affects skin thickness, hair growth, and may contribute to psoriasis and papilloma formation.
385 citations
,
November 1990 in “Journal of Cell Science” Human hair follicles can grow in a lab setting.
133 citations
,
July 1994 in “Journal of Dermatological Science” Human hair growth can be influenced by certain growth factors and has specific metabolic needs.
115 citations
,
February 2016 in “Nature Communications” Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
90 citations
,
February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Interleukin-1 increases keratin K6 production in skin cells.
82 citations
,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
62 citations
,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
58 citations
,
December 1992 in “British Journal of Dermatology” Rat hair follicles grow longer in vitro, but certain factors can inhibit this growth.
57 citations
,
May 2016 in “Matrix Biology” Laminin α5 is essential for skin communication and health.
46 citations
,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
35 citations
,
May 2008 in “Journal of Clinical Oncology” A cancer patient died from a severe skin reaction after taking the drug cetuximab.
32 citations
,
January 2010 in “Journal of Dermatological Science” Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.
29 citations
,
June 2014 in “Experimental Cell Research” EGF–FGF2 helps mouse stem cells grow and become more like nerve cells.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
27 citations
,
June 2001 in “International Journal of Dermatology” MMP-9 increase in hair follicles may lead to hair loss.
26 citations
,
December 2020 in “Genes” A combination of IGF-1 and EGF promotes hair growth in Angora rabbits.
15 citations
,
August 1991 in “Histochemistry and Cell Biology” Enhancing Factor is found in growing tissues like young mouse intestines and skin but not in adults.
13 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
11 citations
,
January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.
10 citations
,
July 2019 in “Advances in Wound Care” Reducing Flightless I protein improves wound healing by activating skin stem cells.
9 citations
,
January 2015 in “Laboratory Animal Research” Laminaria japonica and Cistanche tubulosa extracts combined may effectively promote hair growth.
9 citations
,
December 2013 in “Toxicological Research” Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
8 citations
,
December 2023 in “International Journal of Molecular Sciences” Lower TNF-α levels in PRP may predict better treatment outcomes for bladder conditions.
7 citations
,
April 2018 in “Molecular Medicine Reports” BeauTop helps hair grow by increasing certain growth factors.
6 citations
,
December 2023 in “Journal of Molecular Cell Biology” Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.
5 citations
,
December 2020 in “Gene” ANXA1 influences hair growth in mice through the EGF signaling pathway.
4 citations
,
January 2010 in “Laboratory Animal Research” Sodium silicate helped mouse hair grow similarly to a known hair growth treatment.
2 citations
,
April 2010 in “Cancer Research” Removing EGFR in skin causes inflammation and abnormal hair growth.
2 citations
,
June 2005 in “Clinical Oncology” A man's bald spot grew hair after starting cancer treatment with gefitinib.
1 citations
,
March 2022 in “Daehanhanuihakoeji” Artemisia sieversiana extract may help prevent hair loss and promote hair growth.