June 2010 in “Cell stem cell” Elaine Fuchs aimed to boost global involvement and education in stem cell research as ISSCR president.
96 citations
,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
60 citations
,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
24 citations
,
March 2018 in “Experimental Dermatology” Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.
9 citations
,
June 2017 in “Journal of Cutaneous Pathology” People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.
31 citations
,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
21 citations
,
January 2013 in “Clinical Endoscopy” First Korean case of Cronkhite-Canada syndrome with colon cancer and serrated adenoma.
10 citations
,
May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
37 citations
,
June 2011 in “Journal of The American Academy of Dermatology” Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.
1066 citations
,
March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
165 citations
,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
130 citations
,
November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
75 citations
,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
68 citations
,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
28 citations
,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
25 citations
,
July 2021 in “Journal of Medical Virology” COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.
16 citations
,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
15 citations
,
January 2014 in “Medicinal chemistry” Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
12 citations
,
May 2011 in “Dermatologic Clinics” Hair loss in autoimmune blistering skin diseases varies and may regrow with disease control.
11 citations
,
November 2018 in “Journal of the American Academy of Dermatology” Tofacitinib therapy can effectively regrow eyebrows and eyelashes in some alopecia areata patients.
6 citations
,
December 2017 in “Molecular Medicine Reports” Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.
6 citations
,
July 2009 in “Veterinary dermatology” Vesiculobullous lesions should be considered part of canine cutaneous epitheliotropic T-cell lymphoma.
5 citations
,
January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Porokeratotic eccrine and hair follicle nevus is a very rare skin disorder possibly caused by a GJB2 gene mutation.
October 2023 in “Research Review” Some skin tumors from hair follicles and glands can be linked to genetic syndromes and may be benign or malignant.
January 2020 in “Der Pharmacia Lettre” Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
August 2018 in “International Journal of Research in Dermatology” Skin issues like hair loss, rash, and sensitivity to sunlight are key signs of lupus activity.
June 2018 in “Journal of Dermatological Science” UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.
June 2018 in “Disease-a-Month” Remove inflamed cysts surgically, avoid topical antibiotics on wounds, treat skin and mouth conditions with specific medications, and address underlying causes of hair loss.