research Wound Healing Mechanisms
Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
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research Bioprinting of skin constructs for wound healing
Bioprinting could improve wound healing but needs more development to match real skin.
research Hormone replacement therapy and the skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Estrogens and the skin
Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
research Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
research Epithelial Skin Biology
The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
research From skin microrelief to wrinkles. An area ripe for investigation
Wrinkles form due to structural skin changes and vary in type and treatment response.
research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research Skin ageing
After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
research Promotional Effect of Platelet-Rich Plasma on Hair Follicle Reconstitution in vivo
Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.
research Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact
Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
research Application of multiphoton microscopy in dermatological studies: A mini-review
Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
research Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting
Using adipose tissue-derived fragments improves early skin graft success.
research Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence‐based medicine
Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
research Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine
Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
research The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know?
Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
research Tuning Wnt Signals for More or Fewer Hairs
Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Genetically-manipulated adult stem cells as therapeutic agents and gene delivery vehicle for wound repair and regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Dorsal Skin Reactions of Hairless Dogs to Topical Treatment with Corticosteroids
Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
research Multifaceted role of hair follicle dermal cells in bioengineered skins
Human hair follicle dermal cells can effectively replace other cells in engineered skin.
research PI3K/Akt signaling pathway is essential for de novo hair follicle regeneration
PI3K/Akt pathway is crucial for hair growth and regeneration.
research An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research KERATINS AND SKIN DISORDERS
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Comparisons of mouse models for hair follicle reconstitution
The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
research ILK modulates epithelial polarity and matrix formation in hair follicles
ILK is essential for proper hair follicle development and structure.
research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Tissue Expansion in Cicatricial Alopecia
Tissue expansion is an effective treatment for certain types of hair loss, providing immediate coverage with hair-bearing skin.