38 citations
,
June 2018 in “Plant & cell physiology/Plant and cell physiology” Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
January 2026 in “PLoS Biology” ARHGEF3 is essential for proper hair follicle development in mice.
30 citations
,
June 2010 in “Endocrine Related Cancer” SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.
January 2024 in “Frontiers in plant science” The zinc finger protein 3 in Arabidopsis thaliana reduces plant growth and root hair development.
56 citations
,
March 2017 in “Plant and Cell Physiology” Light sheet fluorescence microscopy effectively measures calcium changes in Arabidopsis root hairs.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” 848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.
March 2014 in “Institutional Repositories DataBase (IRDB)” Skin-derived stem cells could help treat skin aging and pigmentation issues.
8 citations
,
June 2016 in “Journal of Cutaneous Pathology” Two women were diagnosed with a rare melanoma that looked like hair loss but was actually a type of skin cancer.
A rare case of a benign hair follicle tumor with unusual skin changes highlights the need for timely diagnosis to prevent potential cancer.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
48 citations
,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
46 citations
,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
38 citations
,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
16 citations
,
August 2022 in “Nature Communications” ROR2 is essential for hair follicle stem cell renewal and maintenance.
16 citations
,
January 2016 in “International Journal of Medical Sciences” Wnt5a slows down hair growth by blocking a specific pathway during hair regeneration.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
8 citations
,
May 2017 in “IUBMB life” Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.
8 citations
,
December 2016 in “Revista Medica De Chile” Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
4 citations
,
January 2020 in “Frontiers in Physiology” Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.
4 citations
,
April 2018 in “Journal of Investigative Dermatology” Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.
3 citations
,
October 2024 in “Frontiers in Medicine” Sun-exposed skin shows different cell activity and gene expression, suggesting targets to prevent skin aging and cancer.
2 citations
,
June 2021 in “Notulae Botanicae Horti Agrobotanici Cluj-Napoca” More research is needed to understand how nutrients affect root hair growth.
May 2026 in “Research Square” The polyG fragment in Hoxc13 protein helps evolve mammalian skin and hair by enhancing gene interactions.
April 2018 in “Journal of Investigative Dermatology” Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
April 2018 in “Journal of Investigative Dermatology” Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
April 2018 in “Journal of Investigative Dermatology” Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Certain nutrients can improve skin health and treat skin problems safely.
8 citations
,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
6 citations
,
January 2020 in “Czech Journal of Animal Science” The FAT1 gene and its variations can help improve wool quality in Chinese Merino sheep through selective breeding.