research Serotoninergic and melatoninergic systems are fully expressed in human skin
Human skin can make serotonin and melatonin.
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research Effects of EGF on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles
EGF makes hair follicles grow longer but stops hair production.
research Topical application of synthetic melanin promotes tissue repair
Synthetic melanin applied to skin speeds up wound healing.
research In vitro methodology, hormonal and nutritional effects and fibre production in isolated ovine and caprine anagen hair follicles
Angora goat hair grows faster and produces more protein than cashmere goat hair, and certain hormones and nutrients positively affect hair growth and protein synthesis.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Hair growth control by innate immunocytes: Perifollicular macrophages revisited
Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
research Comparative biology of tissue repair, regeneration and aging
The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
research Hairless-knockout piglets generated using the clustered regularly interspaced short palindromic repeat/CRISPR-associated-9 exhibit abnormalities in the skin and thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity
AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
research Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles
AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research New potential antiscarring approaches
New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.
research The effects of gamma rays on the regeneration of hair follicles are carried over to later hair cycles
Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
research Revisiting the significance of keratin expression in complex epithelia
Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
research Wound healing
Wound healing is complex and requires more research to enhance treatment methods.
research Severe cutaneous adverse reactions to drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness
Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
research Novel therapeutic approaches in utilizing platelet lysate in regenerative medicine: Are we ready for clinical use?
Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research A review of cellular biopreservation considerations during hair transplantation
Proper cell preservation is crucial for successful hair transplants and other medical treatments.
research Preparing regenerative therapies for clinical application: proposals for responsible translation
The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.
research LncRNA-miRNA-mRNA regulatory networks in skin aging and therapeutic potentials
ceRNA networks offer potential treatments for skin aging and wound healing.
research A comparative study of materials assembled from recombinant K31 and K81 and extracted human hair keratins
Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
research Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles
Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.
research Activation of the integrated stress response in human hair follicles
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
research INVESTIGATING THE MECHANISMS UNDERLYING THE PATHOGENESIS OF ALOPECIA AREATA
Alopecia areata may be treated by using EGCG to balance immune cells and reduce inflammation.
research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis
Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
research Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture
Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.