research The upper dermal sheath has a potential to regenerate the hair in the rat follicular epidermis
The upper dermal sheath can regenerate hair in rats.
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630-660 / 1000+ resultsresearch Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems
GLI and EGF signalling affect Basal Cell Carcinoma development and could be therapeutic targets.
research [An immunohistochemical study on cell differentiation in the outer root sheath of the normal human anagen hair follicles with antikeratin monoclonal antibodies].
Keratinocytes in hair follicles differentiate similarly to skin cells, with specific patterns in different regions.
research Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo
New mouse models help study melanocytic cells for melanoma research.
research A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.
Keratin expression reflects cell organization and differentiation, not causes it.
research The hair cycle and Vitamin D receptor
Vitamin D receptor is essential for healthy hair growth.
research 132 Design of an in vitro skin 3D model mimicking a disruption of the barrier function
Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
research Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research The effect of flavonoids on regenerated hair follicles with pigmentation
Certain flavonoids can improve the growth of pigmented hair in mice.
research Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation
Hair follicle cells resist turning into skin cells.
research Controversial Concepts
The author now believes tricholemmal carcinoma is a rare type of infundibular squamous cell carcinoma and more research is needed on these tumors.
research Editors' Picks
Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
research Targeted disruption of Bcl‐xL in mouse keratinocytes inhibits both UVB‐ and chemically induced skin carcinogenesis
Disrupting Bcl-xL in mice reduces skin cancer risk.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research NG2 Proteoglycan Expression in Mouse Skin: Altered Postnatal Skin Development in the NG2 Null Mouse
NG2 is crucial for normal skin and hair development in mice.
research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Dlx3 is a crucial regulator of hair follicle differentiation and cycling
Dlx3 is essential for hair growth and regeneration.
research Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice
N-WASP is essential for normal hair growth in mice.
research Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata
Regenerative therapies show promise for treating vitiligo and alopecia areata.
research Sox13 is a novel early marker for hair follicle development
Sox13 is a useful marker for early hair follicle development but not essential for hair growth.
research Does fat get you skinny?
Fat may help skin health and repair, but more research is needed.
research Bilayer Silk Fibroin/Sodium Alginate Scaffold Delivered hUC-MSCs to Enhance Skin Scarless Healing and Hair Follicle Regeneration with the IRE1/XBP1 Pathway Inhibition
The scaffold helps wounds heal without scars and promotes hair growth.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived stem cell melanocytes could be a promising treatment for vitiligo.
research Implications of constitutively active bone morphogenetic protein (BMP) signaling in skin morphogenesis and skin postnatal homeostasis
High BMP signaling disrupts hair growth and balance in skin cells.
research Regenerating Hair Follicles
Healing skin wounds in mice can create new hair follicles, and adjusting Wnt signaling could potentially reduce scarring and treat hair loss.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research Silk Fibroin-Based Hydrogel Microneedles Deliver α-MSH to Promote Melanosome Delivery for Vitiligo Treatment
Silk fibroin microneedles can effectively treat vitiligo by promoting skin pigmentation.
research Skin Wound Healing
Using a specific binding agent and low doses of FK506 can stimulate stem cells, speeding up skin healing by 25% and improving skin quality in rats and mice.
research Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy
Anti-EGFR therapy can cause skin issues, but FGF7 treatment might help.
research Advances in Microengineered Platforms for Skin Research
Skin-on-a-chip devices better mimic human skin for research.