Sheep can lose wool quickly due to stress, but it doesn't cause itching or pain.
February 2014 in “PubMed” Modified rat hair follicle stem cells can help create artificial hair follicles, blood vessels, and skin.
2 citations
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August 2012 in “Journal of the American Academy of Dermatology” Two patients with the same genetic mutation had both blistering skin and easily pulled out hair.
39 citations
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
61 citations
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September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
19 citations
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September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
4 citations
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March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
62 citations
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April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
11 citations
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January 2013 in “Methods in molecular biology” The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
10 citations
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May 1978 in “Acta Dermato Venereologica” Pustules in toxic erythema are linked to hair follicles or sweat ducts.
7 citations
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November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
6 citations
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September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
April 2017 in “Journal of Investigative Dermatology” The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
May 2011 in “British Journal of Dermatology” The 1891 epidemic skin disease was likely caused by arsenic poisoning, possibly from beer or fish.
April 2017 in “Journal of Investigative Dermatology” Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
396 citations
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May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
134 citations
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January 2011 in “Development” Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
83 citations
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January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
83 citations
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May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
63 citations
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January 1984 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth by increasing cell division and DNA synthesis.
61 citations
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November 2004 in “Annals of the Academy of Medicine Singapore” Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
50 citations
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September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
46 citations
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June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
42 citations
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October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
39 citations
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January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
38 citations
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July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
32 citations
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June 2012 in “PLoS ONE” Blocking IL-8 can reduce skin rashes from cancer treatment.
31 citations
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September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
28 citations
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December 2018 in “Plant, cell & environment/Plant, cell and environment” A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.