research Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera.
A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
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research Alteration of Skin Properties with Autologous Dermal Fibroblasts
Using your own skin cells can help repair aging skin and promote hair growth.
research Use of Induced Pluripotent Stem Cells in Dermatological Research
iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research A Systematic Review of Case Series and Clinical Trials Investigating Regenerative Medicine for the Treatment of Vitiligo
Regenerative medicine is effective and safe for treating vitiligo.
research What’s new in the treatment of vitiligo
New treatments for vitiligo show promise but still face challenges, especially for hands and feet.
research TGF-β family signaling in stem cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells
Scientists created feather buds in lab-grown chick skin using specific cell interactions.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Cultured Human Foreskin as a Model System for Evaluating Ionizing Radiation-Induced Skin Injury
Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
research Keratin cytoskeletons in epithelial cells of internal organs
Keratins provide structural strength in epithelial cells and help identify cell origins.
research β-Catenin is involved in oleanolic acid-dependent promotion of proliferation in human hair matrix cells in an in vitro organ culture model
Oleanolic acid promotes hair growth by increasing cell proliferation through the Wnt/β-catenin pathway.
research DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
research Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts
Wnt signaling is disrupted in asthma, affecting cell growth and inflammation.
research Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages
The skin can still regenerate and function well even with fewer fibroblasts.
research Considerations in the choice of a skin donor site for harvesting keratinocytes containing a high proportion of stem cells for culture in vitro
P-auricular skin is the best donor site for high stem cell content in keratinocyte cultures.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research Hair follicle regeneration in vitro
Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
research Follicular dermal papilla structures by organization of epithelial and mesenchymal cells in interfacial polyelectrolyte complex fibers
Scientists created 3D hair-like structures that could help study hair growth and test treatments.
research In vitro identification of a stem cell population from canine hair follicle bulge region
Researchers found stem cells in dog hair follicles using specific markers.
research Identification and dissection of an enhancer controlling epithelial gene expression in skin
A specific DNA region controls skin cell gene expression by working with certain proteins.
research Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids
A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
research Role of boundary conditions in an experimental model of epithelial wound healing
Mast cells and VEGF contribute to post-surgery adhesions, and blocking VEGF can reduce these adhesions; also, certain factors affect wound healing and fetal skin heals differently with age.
research The metabolism of testosterone by dermal papilla cells cultured from scalp follicles of men with androgenetic alopecia
Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
research Application and Progress of Cultured Models of Gallbladder Carcinoma
Advancements in cultured models improve understanding and treatment of gallbladder cancer.
research The Role of Vimentin in Tissue Repair and Cell Growth
Vimentin is crucial for wound healing, cell growth, and managing immune responses.
research Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin
Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.