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October 2007 in “Wound Repair and Regeneration” Epidermal stem cells maintain skin health through specific niches and signaling pathways.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
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June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
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September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
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October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MOF controls skin development by regulating genes for mitochondria and cilia.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
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April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers identified new cell types and genes in early hair follicle development.
August 2016 in “Journal of Investigative Dermatology” EZH2 is essential for hair growth and skin cell development.
January 2008 in “The Year book of dermatology” After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.
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May 2022 in “International journal of molecular sciences” Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
Low IRES/Cap translation is linked to higher stem cell potential.
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February 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b helps skin cells develop into hair-related structures.
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October 2017 in “Oncotarget” Gsdma3 affects hair growth by controlling Wnt5a, which influences hair cell development.
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February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
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August 2002 in “BioEssays” The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
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November 1989 in “The Journal of Cell Biology” Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
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December 2007 in “Journal of Otology” Guinea pig fat stem cells can become hair cell-like cells in a lab.
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October 2009 in “Veterinary Dermatology” Canine claws have complex structures with different keratin types, similar to hair and nails.
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February 1982 in “Australian Journal of Biological Sciences” Epithelial cells from young rat hair follicles grow and form aggregates in culture, but don't produce hair keratin proteins.
January 2016 in “eScholarship (California Digital Library)” HBCs in the olfactory epithelium can self-renew or differentiate into other cell types, with specific patterns during regeneration.
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November 2013 in “Nature” Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
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February 1991 in “Development” Fos protein is crucial for cell transition to cornification in keratinized tissues.
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
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July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.