4 citations
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October 2017 in “Advances in tissue engineering & regenerative medicine” Researchers created a potential skin substitute using a biodegradable mat that supports skin cell growth and layer formation.
January 2025 in “Frontiers in Cell and Developmental Biology” Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
11 citations
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October 2001 in “Tissue engineering” Cultured epithelium can form hair follicles when combined with dermal papillae.
40 citations
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June 2013 in “Biomaterials” Scientists created 3D hair-like structures that could help study hair growth and test treatments.
15 citations
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August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
3 citations
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September 2023 in “Frontiers in immunology” Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
64 citations
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August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
9 citations
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April 2006 in “American Journal of Pathology” SGK3 is essential for proper hair growth and health.
124 citations
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December 1988 in “Differentiation” Trichocytic differentiation starts in cells with epithelial cytokeratins, transitioning to trichocytic cytokeratins in hair and gradually in nails.
52 citations
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October 2005 in “Journal of Investigative Dermatology” Hair follicle stem cells have greater longevity and adhesion, while transit-amplifying cells are more mobile.
92 citations
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June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
29 citations
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March 2015 in “Journal of Investigative Dermatology” Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.
32 citations
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February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
98 citations
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December 2003 in “The FASEB Journal” Thymosin β4 promotes hair growth by activating stem cells in hair follicles.
36 citations
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May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
5 citations
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July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
December 2016 in “Paleontological Journal” Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
53 citations
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January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
218 citations
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January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
130 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
49 citations
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November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
42 citations
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March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
39 citations
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December 2011 in “PLoS ONE” Radiofrequency exposure can stimulate hair growth by increasing IGF-1 in hair follicle cells.
28 citations
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November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
26 citations
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October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
19 citations
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July 2015 in “Journal of Ginseng Research” Korean Red Ginseng may protect against hair loss caused by chemotherapy.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Cilostazol may help hair grow and could be a new treatment for hair loss.
April 2021 in “Journal of Investigative Dermatology” Leontopodium alpinum extract may help reduce hair shedding by keeping hair in the growth phase longer.
135 citations
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December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
120 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.