August 2018 in “Journal of Investigative Dermatology” Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.
August 2018 in “Journal of Investigative Dermatology” A woman with dermatomyositis improved after treatment for neck panniculitis, suggesting similar treatment for related conditions.
August 2018 in “Journal of Investigative Dermatology” The conclusion is that using light-sheet fluorescence microscopy with a special solution can effectively create detailed 3D images of human skin for dermatological research.
November 2020 in “International journal of contemporary pediatrics” Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
68 citations
,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
66 citations
,
December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
31 citations
,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
17 citations
,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
12 citations
,
July 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
11 citations
,
October 2018 in “The Journal of Dermatology” Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
9 citations
,
March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
7 citations
,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
6 citations
,
February 2012 in “American Journal of Animal and Veterinary Sciences” Growth factors are crucial for hair follicle growth and development.
4 citations
,
February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
2 citations
,
December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
2 citations
,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
April 2024 in “The Indonesian Biomedical Journal” Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
1039 citations
,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
43 citations
,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
Ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes and influencing hair follicle phases.
Ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes and influencing hair follicle phases.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
Ocu-miR-205 affects hair density in Rex rabbits by influencing cell processes and signaling pathways.
145 citations
,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
65 citations
,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.