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The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.

Immune cells boost stem cell activity in hairy moles, causing more hair growth.

A new therapy for a skin blistering condition has not been developed yet.

High TSPEAR levels in colorectal cancer predict worse outcomes.

The enzyme is crucial for skin cell development and can be activated without proteolytic activation.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.

Skin RAGE levels are linked to inflammation and cell death.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.

Researchers found a non-functional sheep keratin gene due to mutations.

E6/E7 oncogenes in hair follicles cause continuous hair growth by skipping the resting phase.

Colorectal cancer's ability to spread is due to changes in many genes, not just one.

A rare gene mutation causes skin fragility and itching without affecting hair or nails.

Cholesteatoma shows abnormal and increased EGF receptor expression, indicating its rapid growth.

Antibodies help identify glycoproteins in normal skin and tumor cells.

A new microneedle patch significantly improves melanoma treatment by using a special material to activate cancer-fighting drugs and disrupt cancer cells.

ANE syndrome is caused by a mutation in the RBM28 protein that disrupts ribosome assembly.

Blocking IL-8 can reduce skin rashes from cancer treatment.

mEphA1 receptor tyrosine kinase is important for skin and hair development and may play a role in certain diseases.

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

PRAME is often present in Paget disease and could help in diagnosis, but more research is needed.

Activated erbB-2 in mice skin causes severe skin and hair abnormalities.

Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.

NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.

Peptide drugs now target hard-to-reach proteins more effectively and specifically.