1 citations
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September 2019 in “Journal of Investigative Dermatology” The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
39 citations
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December 1998 in “Journal of Cell Science” The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
147 citations
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April 1997 in “Oncogene” Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” YAP1 is important for skin regeneration and may affect skin disorder treatments.
15 citations
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January 2017 in “Polymers” Polyelectrolytes can improve cell surfaces for better medical applications.
1 citations
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April 2010 in “Cancer Research” WYE-130600 may cause skin thickening and irritation.
MSC-CM cream speeds up burn wound healing better than the control treatment.
28 citations
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January 2015 in “Journal of Cell Science” PINCH-1 is crucial for skin cell adhesion and movement, working with EPLIN and ILK.
January 2005 in “世界胃肠病学杂志:英文版(电子版)” Etoposide makes radiation therapy more effective against tumors without major side effects.
1 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
10 citations
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December 1990 in “Archives of Dermatological Research”
17 citations
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May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
The microenvironment affects the behavior and survival of melanocytes with the GNAQ oncogene in melanoma.
CD28 is a promising target for treating alopecia areata with belatacept.
CD28 is a promising target for treating alopecia areata with belatacept.
The study identified a key protein involved in producing underarm odor and found ways to inhibit it.
5 citations
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September 2018 in “Journal of Investigative Dermatology” Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
21 citations
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December 1994 in “Journal of Investigative Dermatology”
February 2025 in “Journal of the European Academy of Dermatology and Venereology” Erosive pustular dermatosis of the scalp can occur about 17 weeks after starting EGFR inhibitors, and early minocycline may help manage it.
24 citations
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October 2019 in “Genes” A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
43 citations
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April 2010 in “Developmental Biology” Sebaceous glands can form new hair follicles when activated, but hair follicle bulges cannot.
6 citations
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July 2009 in “Veterinary dermatology” Vesiculobullous lesions should be considered part of canine cutaneous epitheliotropic T-cell lymphoma.
26 citations
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June 2003 in “PubMed” Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
March 2011 in “Journal of Dermatology” The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.
13 citations
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December 2001 in “Journal of Investigative Dermatology” Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
33 citations
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March 1994 in “PubMed” High ODC and low K1 and K10 may indicate early skin tumors in mice.
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June 2025 in “Cell Reports” Clonally expanded CD8+ T cells cause alopecia areata.
April 2021 in “Journal of Investigative Dermatology” People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.