August 2016 in “Journal of Investigative Dermatology” The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.
May 2025 in “Experimental Dermatology” A new genetic tool improves the study of hair growth and potential hair disorder treatments.
48 citations
,
March 1993 in “The Laryngoscope” Cholesteatoma shows abnormal and increased EGF receptor expression, indicating its rapid growth.
January 2026 in “Biomaterials”
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Prss53 affects hair shape and bone development in rabbits.
29 citations
,
June 2014 in “Experimental Cell Research” EGF–FGF2 helps mouse stem cells grow and become more like nerve cells.
17 citations
,
August 2012 in “Journal of Medical Genetics” A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.
12 citations
,
September 2021 in “PLoS ONE” WNT10A and EBF1 interaction affects hair growth in male-pattern baldness.
23 citations
,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
March 2026 in “Journal of Investigative Dermatology” 10 citations
,
December 2018 in “Medical Science Monitor” The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.
14 citations
,
January 2005 in “Cell Stress and Chaperones” The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
2 citations
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August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
30 citations
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October 1999 in “Differentiation” Mutant MK6a transgenes in mice cause blistering, hair loss, and potential human alopecia.
21 citations
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December 1994 in “Journal of Investigative Dermatology” January 2009 in “China Practical Medicine” Certain genes help dermal papillae cells in hair follicles grow and group together.
46 citations
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November 2004 in “Lipids” PPARs help regulate skin health and could be used to treat skin disorders.
January 2012 in “Journal of Northwest A & F University” The Eda gene helps regulate the hair cycle in goats.
66 citations
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February 2013 in “PeerJ” Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.
2 citations
,
August 2013 in “British Journal of Dermatology” Chemotherapy improved a girl's painful foot condition linked to pachyonychia congenita.
2 citations
,
September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
January 2026 in “Frontiers in Medicine” PP-PTKL may help treat hair greying, but more testing is needed.
126 citations
,
October 2012 in “PLoS ONE” Reduced cytokinin levels help plants adapt to low potassium by increasing root hair growth and potassium uptake.
August 2009 in “Mechanisms of Development” 5 citations
,
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The gene therapy showed significant wound healing and was safe for treating severe RDEB.
November 2024 in “Journal of Investigative Dermatology”
1 citations
,
May 2025 in “Natural Products and Bioprospecting” PEVIII is a promising treatment for Pseudomonas aeruginosa keratitis.
98 citations
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May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
29 citations
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June 2015 in “Kidney International” Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.