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EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.

Reversed sequential therapy with cyproterone acetate was effective for treating women with hirsutism and related conditions.

Finasteride may help reduce COVID-19 infection by altering a key gene.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.

ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.

Cyproterone acetate with ethynyl estradiol significantly improved acne and seborrhea in women, but was less effective for hair loss and excessive hair growth.

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

5α-reductases increase epitestosterone's effect on androgen receptors.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.

Certain plant compounds can help prevent and treat a virus in pigs.

SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.

Rimegepant causes more nausea and skin issues, while ubrogepant causes more muscle issues; personalized treatment is important.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

A new compound was made that might help treat diseases related to male hormones.

Researchers found several compounds that could potentially treat Zika virus.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

The treatment cleared psoriasis in some patients but caused side effects in most.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.