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PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

A girl with Becker's nevus syndrome showed good improvement in breast development using spironolactone.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Genetic mutations linked to ectodermal dysplasias and hair loss were identified in Pakistani families.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

TACE/ADAM17 is essential for maintaining healthy hair and hair follicle stem cells.

Increased TEMRA cells can predict treatment outcomes in rapidly progressive alopecia areata.

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.

Skin cancer often starts from Lgr5+ progenitor cells.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.

High levels of ornithine decarboxylase can cause tumors in mouse skin.

Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.

Dab2 protein is crucial for hair follicle stem cell renewal and preventing early aging.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.

RORA may help regulate hair growth by affecting hair follicle stem cells.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.

Nephronectin is linked to worse breast cancer outcomes and helps cancer spread.

The HR protein's role as a repressor is essential for controlling hair growth.

Certain immune markers may predict chemotherapy response in mesothelioma, and nivolumab is a tolerable and effective treatment for advanced non-small cell lung cancer.

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.