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ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.

Androgen receptors help prostate cancer cells grow and resist drugs.

RC48 shows promise for treating certain advanced cancers, but more research is needed.

Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

RXRα is crucial for hair growth and skin cell function.

RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.

New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.

c-Kit is important for heart regeneration and cancer development.

Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.

Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

Targeting amphiregulin may improve treatment for fibrosis and cancer.

Mice with human-like EGFR had growth issues, skin defects, heart problems, and unusual bone development.

Changing YBX1 protein activity affects skin stem cell function and aging.

Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.

Tsc2-deficient stem cells can help understand and treat TSC-related tumors.

Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.

EGF signaling affects gene expression in skin cells, influencing hair growth and potentially cancer.

ROR2 is crucial for hair follicle stem cell maintenance and self-renewal.

Blocking mTORC1 reduces skin tumor growth in mice.

Wnt signaling is crucial for Hedgehog-driven skin tumor growth.

NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.

Recognizing RSCC is crucial due to its aggressive nature and high risk of poor outcomes.

Lack of vitamin D receptor increases skin tumor risk by boosting hedgehog signaling.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.