17 citations
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August 2012 in “Journal of Medical Genetics” A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.
May 2025 in “Experimental Dermatology” A new genetic tool improves the study of hair growth and potential hair disorder treatments.
3 citations
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August 2020 in “International Journal of Molecular Sciences” Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
18 citations
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October 2013 in “Stem Cell Research & Therapy” A specific combination of chemicals effectively expands genetically modified skin cells for potential use in skin therapy.
October 2025 in “Proceedings of the National Academy of Sciences” Phospholipids help plant proteins move by regulating receptor interactions.
Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.
April 2026 in “Frontiers in Cell and Developmental Biology” GPCRs are vital for wound healing by affecting cell growth and immune response.
135 citations
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January 1996 in “Journal of Investigative Dermatology” September 2025 in “Science Advances” PADI4 enzyme slows down cell growth in developing hair follicles.
Ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes and influencing hair follicle phases.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
83 citations
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October 2016 in “Stem Cells and Development” Epidermal growth factor helps hair stem cells grow by activating specific cell pathways.
September 2025 in “Genes & Diseases” Lgr6+ cells are important for tissue repair and could be a target for treating cancer and other diseases.
February 2025 in “Journal of Clinical Investigation” RNase L hinders hair growth by altering immune signals.
January 2005 in “Enlighten: Publications (The University of Glasgow)” Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
December 2004 in “PLoS ONE” The Foxn1(-/-) phenotype disrupts hair growth and affects skin stem cells.
39 citations
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October 2012 in “Familial cancer” New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
56 citations
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September 2014 in “Molecular Endocrinology” Vitamin D receptor is essential for hair growth signaling.
Meis2 is essential for touch sensation and nerve function in mice.
PDGF signaling is crucial for cell development, wound healing, and fluid regulation in the body.
1 citations
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November 2024 in “EMBO Reports” Deleting Gpr54 speeds up hair growth and regeneration.
215 citations
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November 2000 in “Journal of Investigative Dermatology” The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
April 2026 in “Stem Cell Reviews and Reports” 37 citations
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April 2018 in “Journal of Allergy and Clinical Immunology” A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.
6 citations
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November 2022 in “Antioxidants” OR2AT4 helps reduce aging and cell damage in human skin cells.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” ACA2 is crucial for root hair growth by controlling calcium levels in cells.
4 citations
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October 2018 in “Cell Stem Cell” Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.