18 citations
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February 2012 in “Experimental Dermatology” No link found between specific genes and female pattern hair loss.
May 2026 in “Frontiers in Pharmacology” The study investigates the effects of Dendrobium officinale polysaccharide (DOP) on hair regrowth in androgenetic alopecia (AGA) mice. Results indicate that DOP improves hair regrowth in a dose-dependent manner, with the high-dose group showing significant improvements in hair coverage, follicle density, dermal thickness, hair bulb diameter, and anagen phase proportion. The treatment was linked to decreased SRD5A1 expression, increased CYP19A1 expression, reduced local dihydrotestosterone and testosterone levels, and elevated p-ESR1 and KRT28/KRT71 expression. These changes suggest that DOP influences local steroid metabolism, ESR1 activation, and keratin-related follicular responses, enhancing follicular morphology and cycling. The findings propose a framework for further exploration of DOP in treating AGA.
Finasteride may affect female fertility by altering gene activity.
November 2022 in “Scientific Reports” Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.
77 citations
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April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
15 citations
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June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
13 citations
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October 2024 in “Scientific Reports” Early diagnosis and personalized treatment for PCOS are crucial, especially for young women in West Bengal, India.
3 citations
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June 2017 in “Reproductive biomedicine online” A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.
3 citations
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February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
February 2026 in “Scientific Reports” Platycladi Cacumen may help treat hair loss by affecting certain biological pathways.
January 2026 in “Scientific Reports” Sesamin may help treat hair loss by affecting specific cell pathways.
December 2025 in “International Journal of Molecular Sciences” Opophytum forskahlii seed oil may help with anti-aging and hair growth.
Platycladi Cacumen may help treat hair loss by targeting specific proteins and pathways.
Baicalin may effectively treat hair loss by inhibiting 5α-reductase.
June 2024 in “Research Square (Research Square)” Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
November 2022 in “Research Square (Research Square)” The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.
1 citations
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April 2025 in “Tropical Journal of Natural Product Research” Avicennia marina shows potential to treat Hepatitis C by targeting key proteins.
February 2026 in “Applied Biosciences” The study found potential new DNA patterns in fertility genes, but further testing is needed.
November 2025 in “Drug Testing and Analysis” Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.
4 citations
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December 2013 in “British Journal of Dermatology” ESR2 gene linked to female-pattern hair loss.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Esrp1 is important for skin health by helping form and maintain the skin barrier.
25 citations
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November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
68 citations
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April 2014 in “Journal of Molecular Endocrinology” The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
87 citations
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March 2011 in “Australasian Journal of Dermatology” Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.
32 citations
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February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
10 citations
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February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
3 citations
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September 2019 in “PLOS ONE” Genetic variations affect dutasteride treatment response for male pattern hair loss.
1415 citations
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October 2007 in “European Journal of Epidemiology” The Rotterdam Study investigates diseases in older adults and has produced many research findings.
532 citations
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August 2011 in “Journal of the American Academy of Dermatology” Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
359 citations
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September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.