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A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.

Method accurately measures finasteride concentration in medicine.

Finasteride delivery through skin improved using invasomes and iontophoresis.

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Cysteine helps maintain keratin production in skin cells even when iron is low.

A new mutation in the STS gene causes X-linked ichthyosis, even in rare female cases.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

The developed nasal gel improves cilostazol delivery to the brain, enhancing its effectiveness and reducing side effects.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.

Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.

Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.

Ethosomes deliver finasteride through the skin more effectively than liposomes.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

A new mouse mutation causes skin and hair defects due to a gene change.

Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.

Certain peptides can prevent hair loss in young rats caused by a cancer drug.

Transamidases are present in the epidermis but their exact role is unclear.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.