research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
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research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Radioprotection of Lung Tissue by Soy Isoflavones
Soy isoflavones can protect lung tissue from radiation damage.
research Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women
Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
research Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate
Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
research Physiologic changes and dermatoses of pregnancy
Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.
research Enhancement of percutaneous absorption of Finasteride by cosolvents, cosurfactant and surfactants
Transcutol P best increases Finasteride absorption for hair loss treatment.
research The effects of lovastatin on conventional medical treatment of lower urinary tract symptoms with finasteride
Lovastatin doesn't improve lower urinary tract symptoms treatment.
research Applications of steroid drugs entrapped in cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research The efficacy and use of finasteride in women: a systematic review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
research Male hormonal contraception: looking back and moving forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing
KLF4 is important for maintaining skin stem cells and helps heal wounds.
research Evaluation of androgen receptor gene as a candidate gene in female androgenetic alopecia
AR gene not major factor in female hair loss; different from male hair loss.
research Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: What is in common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Use of Hair Products Containing Hormone or Placenta by US Military Personnel
About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.
research Management of Androgenetic Alopecia
Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.
research Androgenic effects of oral contraceptives: Implications for patient compliance
Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.
research Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride
Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
research Testosterone implants in women: Pharmacological dosing for a physiologic effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Identification of Telogen Markers Underscores that Telogen Is Far from a Quiescent Hair Cycle Phase
Telogen is an active phase with important biological processes, not a resting phase.
research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
research Current evaluation of amenorrhea
Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.
research Pharmacologic Treatment of Polycystic Ovary Syndrome
The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
research Comparative Analysis of Machine Learning Algorithms in Diagnosis of Polycystic Ovarian Syndrome
The Random Forest algorithm was the most accurate at diagnosing Polycystic Ovarian Syndrome.
research Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research Expression of androgen receptor coactivator ARA70/ELE1 in androgenic alopecia
The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
research A comparative study of Aldactone® and Diane® in the treatment of hirsutism
Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
research The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research Promotion Effect of Apo-9′-fucoxanthinone from Sargassum muticum on Hair Growth via the Activation of Wnt/β-Catenin and VEGF-R2
Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.