research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
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research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
The research identified new skin traits in mice, some linked to human skin conditions.
research Tamoxifen for flutamide/finasteride-induced gynecomastia
Tamoxifen effectively treats gynecomastia without causing impotence.
research Alopecia Areata
Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles
Minoxidil works in liver and outer hair root sheath for hair growth.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research TREATMENT OF FEMALE ANDROGENETIC ALOPECIA WITH MINOXIDIL 2%
Minoxidil 2% effectively treats female hair loss, promoting growth and density.
research Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review
Quercetin may help with PCOS symptoms, but more research is needed.
research Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats
Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
research Male pattern baldness: current treatments, future prospects
Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
research Hair loss and herbs for treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Treatment options for alopecia: an update, looking to the future
The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
research Higher PDCD4 expression is associated with obesity, insulin resistance, lipid metabolism disorders, and granulosa cell apoptosis in polycystic ovary syndrome
More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.
research Pathophysiology of the Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
research Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
research Stress-induced c-Jun-dependent Vitamin D Receptor (VDR) Activation Dissects the Non-classical VDR Pathway from the Classical VDR Activity
Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
research Female pattern hair loss, sebum excretion and the end-organ response to androgens
Hair loss in women not always linked to increased oil production; other factors may be involved.
research Modeling of chronic radiation-induced cystitis in mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata
Gonadal hormones significantly affect the severity of alopecia areata in mice.
research ANDROGENETIC ALOPECIA
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research Dietary isoflavone increases insulin-like growth factor-I production, thereby promoting hair growth in mice
Eating isoflavone can help mice grow hair by increasing a growth factor.
research HaCaT Cell Proliferation Influenced by Melatonin
Melatonin affects skin cell growth differently based on how much and how long it's used.
research Cardiometabolic profile of young women with hypoprolactinemia
Low prolactin in young women may increase heart and metabolism risks.
research Natural products reverse cancer multidrug resistance
Natural products can help overcome cancer drug resistance.