research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
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research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results
5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
research Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials
Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.
research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
research Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia
Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.
research Interventions for androgenic alopecia in women
Review finds no permanent solution for female hair loss.
research Hormonal Therapy for Acne
Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
research EFFECTS OF HORMONAL THERAPY IN TRANSGENDERS
Hormonal therapy for transgender individuals carries health risks but is a personal choice.
research An affirming approach to caring for transgender and gender-diverse youth
The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.
research New onset of alopecia in a young woman with end-stage renal disease
A young woman with kidney failure had hair loss due to a common hormonal disorder, which improved with hormone therapy.
research Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha
Minoxidil might partially activate estrogen receptors, affecting hair growth.
research In-silico screening of potential anti-androgenic and anti-estrogenic phytocompounds from Saraca asoca for polycystic ovary syndrome treatment
Procyanidin B2 and leucopelargonidin from Saraca asoca may help treat PCOS by balancing hormones.
research Medical care for children and adolescents with gender dysphoria and gender inconsistency in the light of current recommendations - how to implement the "primum non nocere" principle?
The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
research Fundamentals
Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
research Formestane Preferred as Second-Line Therapy in Advanced Breast Cancer
Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Is dehydroepiandrosterone a hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Is COVID-19 Gender-sensitive?
Men have more severe COVID-19 outcomes than women.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research A role of melatonin in neuroectodermal‐mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors
Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
research Estrogen Receptor α, but not Estrogen Receptor β, is Involved in the Regulation of the Hair Follicle Cycling as well as the Thickness of Epidermis in Male Mice
Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
research The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta?
Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
research HRT for women with premature ovarian insufficiency: a comprehensive review
The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.
research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
research The therapeutic use of androgens in women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Testosterone therapy for sexual dysfunction in postmenopausal women
Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
research Are sex discordant outcomes in COVID-19 related to sex hormones?
Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
research Estrogen Leads to Reversible Hair Cycle Retardation through Inducing Premature Catagen and Maintaining Telogen
Estrogen can temporarily slow down hair growth but this can be reversed.
research 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α
17β-Estradiol slows wound healing in male mice through estrogen receptor-α.
research Neuroactive gonadal drugs for neuroprotection in male and female models of Parkinson's disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.