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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

The Rotterdam Study aims to understand various diseases in older adults.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Noggin is necessary to start the hair growth phase in skin after birth.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Sebocytes play a key role in controlling androgen levels in human skin.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.