September 2023 in “Gynäkologische Endokrinologie” Menopause causes skin and hair to become drier and thinner, but hormone therapy can improve these conditions.
Most postmenopausal women experience significant skin changes and various skin conditions.
November 2011 in “DOAJ (DOAJ: Directory of Open Access Journals)” Oral contraceptives can help manage acne by reducing androgen levels.
March 2023 in “Journal of Cosmetic Dermatology” Low-dose oral minoxidil improved hair growth when topical treatments failed.
80 citations
,
April 2006 in “Clinical Interventions in Aging” Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
3 citations
,
September 2025 in “Frontiers in Cardiovascular Medicine” Women with PCOS have a higher risk of heart disease.
July 2023 in “Journal of Clinical Medicine” Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.
January 2009 in “Gynäkologische Endokrinologie” Minoxidil solution can effectively treat hair thinning in women.
August 2006 in “Experimental dermatology” New treatments targeting insulin, blood flow, and inflammation could improve hormone-related hair conditions with fewer side effects.
186 citations
,
February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
137 citations
,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
131 citations
,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
55 citations
,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
50 citations
,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
49 citations
,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
44 citations
,
June 2017 in “The EMBO Journal” LPA3 signaling in the uterus is crucial for placental formation and fetal development.
26 citations
,
December 2020 in “International Journal of Molecular Sciences” Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.
24 citations
,
July 2016 in “Steroids” Progesterone and testosterone protect brain cells from damage through specific pathways.
24 citations
,
April 2013 in “PLOS ONE” TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
23 citations
,
December 2013 in “Molecular cancer therapeutics” Breast cancer treatments work better with AR activation, improving results and reducing side effects.
21 citations
,
September 2008 in “Brain Research” Neurosteroids in the brain can increase or decrease seizure risk in mice.
19 citations
,
July 2005 in “Steroids” Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.
18 citations
,
January 2019 in “European journal of histochemistry” Cattle skin has leptin which might control skin and hair growth.
13 citations
,
September 2021 in “Current Issues in Molecular Biology” Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.
13 citations
,
October 2019 in “Oncology Reports” The link between anabolic agents and colorectal cancer risk is unclear.
7 citations
,
September 2024 in “Journal of Comparative Effectiveness Research” Palbociclib generally maintains or improves quality of life in advanced breast cancer patients.
7 citations
,
June 2024 in “iScience” Androgens increase cervical cancer risk and affect its development.
7 citations
,
August 2006 in “Maturitas” Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.
6 citations
,
December 2023 in “Journal of Molecular Cell Biology” Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.