research MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
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research The genetics of androgenetic alopecia
Genes and hormones cause hair loss, with four genes contributing equally.
research Treatment of female sexual dysfunction in postmenopausal women—What is the evidence?
Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.
research Menopause and aging, quality of life and sexuality
Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Treatment of hyperandrogenism in polycystic ovary syndrome
Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
research Current concepts in aesthetic endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research AN UPDATED OVERVIEW OF POLYCYSTIC OVARY SYNDROME
Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
research Hirsutism due to polycystic ovarian syndrome: An integrative review of pathophysiology and management
Combining modern and Unani treatments may offer better care for hirsutism in PCOS.
research Major approaches of molecular and physiopathological mechanisms for hormonal treatment of melasma: a systematic review
Estrogens and progesterone are key in regulating melasma pigmentation.
research Endocrine Treatment of Transsexual Persons:An Endocrine Society Clinical Practice Guideline
The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Is COVID-19 Gender-sensitive?
Men have more severe COVID-19 outcomes than women.
research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth
Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
research Lifestyle changes in women with polycystic ovary syndrome
Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
research Androgenetic Alopecia: An Evidence-Based Treatment Update
Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido
DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.
research Mechanism of action of herbs and their active constituents used in hair loss treatment
Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
research Endocrinologic Aspects of Hidradenitis Suppurativa
Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.
research The effect of menopause on the skin and other connective tissues
Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner
Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea
The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
research Trace elements content and hormonal profiles in women with androgenetic alopecia
Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
research Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Comprehensive clinical management of hirsutism
New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
research Acne in Dark Skin
Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.
research Secondary amenorrhea
Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.
research Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
A woman with anorexia and Cushing's syndrome improved after tumor removal, highlighting the need to consider hormonal issues in psychiatric conditions.