33 citations
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May 2017 in “Journal of Clinical Oncology” ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
68 citations
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May 1991 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Both cyproterone acetate and spironolactone effectively reduce hair growth in women with hirsutism.
Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.
6 citations
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January 2020 in “BMC Neuroscience” Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.
September 2021 in “International Journal of Biomedicine” Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
67 citations
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October 2005 in “Annals of Oncology” Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
Stinging nettle infusions improve the strength and antioxidant properties of k-carrageenan hydrogels.
Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.
5 citations
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November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
47 citations
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April 1978 in “Journal of Cutaneous Pathology” Basal cell epithelioma resembles fetal hair follicles, not adult or fetal skin.
November 2025 in “European Journal of Endocrinology” Hair steroid profiling is a feasible, non-invasive alternative to serum analysis for assessing hormone levels and metabolism.
8 citations
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June 2017 in “Steroids” New chemical compounds were made that effectively block an enzyme linked to prostate growth.
1 citations
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November 2024 in “Expert Opinion on Drug Safety” Aromatase inhibitors can cause various adverse reactions, so monitoring is crucial.
78 citations
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January 2000 in “Gynecological Endocrinology” Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
9 citations
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April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
255 citations
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October 1985 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone treatment increases the amount of testosterone available in the body.
25 citations
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June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
187 citations
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December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
19 citations
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June 1999 in “Steroids” Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
8 citations
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June 1995 in “Helvetica Chimica Acta” Compound 15a was effective in inhibiting 5α-reductase.
December 2021 in “Journal of pharmaceutical research international” Spironolactone may be effective for acne and other skin conditions and could be used more in treatment.
January 2023 in “Brazilian Journal of Pharmaceutical Sciences” A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
3 citations
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October 2015 in “EFSA supporting publications” Isoflavones may help with menopause symptoms but could be risky for women with hormone-sensitive cancers.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Spironolactone effectively treats female pattern hair loss but requires ongoing use to maintain results.
44 citations
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December 2005 in “The Journal of Steroid Biochemistry and Molecular Biology” Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.
March 2008 in “The Knowledge Bank (The Ohio State University)” SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.
May 2022 in “Current Enzyme Inhibition” Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
January 2026 in “eKNUTSHIR” Protein-based products are effective for wound healing and have a growing market.
Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.