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Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

Cholesterol transport in hair follicles decreases from growth to regression phase.

Amotosalen-treated donor T-cells can prevent late CMV infection after bone marrow transplants.

PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.

Exosome-enriched vesicles from placental cells improved skin condition in a patient with chronic graft-versus-host disease.

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

A specific gene variation increases the risk of high uric acid and cholesterol in young Mexican males.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

IPM enhances skin penetration of hydrophilic drugs.

Pregnancies in a woman with the Donohue mutation were managed with genetic testing, resulting in three healthy infants.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Artificial sebum L closely mimics human sebum for drug delivery research.

Very-long-chain acyl-CoA synthetases and fatty acid transport proteins play key roles in fatty acid metabolism and lipid processing in different tissues.

Retinoic acid and DMSO improve gene delivery to mouse skin for potential hair and skin disease treatment.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Genetic differences affect breast cancer treatment success with tamoxifen in South African patients.

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.

Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.

Most children with a common hemochromatosis genotype had elevated iron levels but no severe symptoms.

Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.

Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

Tissue-specific variation in mutant load complicates genetic counseling and prenatal diagnosis.

GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.

Amino acid storage proteins are essential for maintaining stem cells in female fruit flies.

Standardized guidelines are needed to improve drug-loaded extracellular vesicle purification.