research Comparison of high-dose finasteride (5 mg/day) versus low-dose finasteride (2.5 mg/day) in the treatment of hirsutism
Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
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research Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome
Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
research An essential role for Rxrα in the development of Th2 responses
RXRα is crucial for proper immune response and links diet to immune function.
research Intermediate filaments: regulation of gene expression and assembly
Intermediate filaments are crucial for cell structure and function, regulated by specific genes and proteins.
research Vitamin D-dependent rickets type II: extreme end organ resistance to 1,25-dihydroxy vitamin D3 in a patient without alopecia
A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
research Hair Loss, Insulin Resistance, and Heredity in Middle-aged Women. a Population-based Study
Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.
research Clinical Manifestations and Management of Acute Thallium Poisoning
Thallium poisoning causes pain, hair loss, and nerve issues, treatable with hemoperfusion and hemodialysis.
research GABAergic neurosteroids mediate the effects of ethanol on long‐term potentiation in rat hippocampal slices
Ethanol blocks memory formation in rats by enhancing certain brain chemicals.
research Sex differences in arterial hypertension
Women may need different blood pressure guidelines than men for heart disease prevention.
research Preparation and characterization of dutasteride-loaded nanostructured lipid carriers coated with stearic acid-chitosan oligomer for topical delivery
The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
research Chrousos syndrome: from molecular pathogenesis to therapeutic management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Terrestrial vertebrates have two keratin gene clusters; striking differences in teleost fish
Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
research A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism
Spironolactone plus finasteride reduces hirsutism more effectively.
research Two siblings with vitamin-D-dependent rickets type II: No recurrence of rickets for 14 years after cessation of therapy
Two siblings stayed rickets-free for 14 years after stopping treatment.
research Platelet-rich plasma injection is effective and safe for the treatment of alopecia
Injecting platelet-rich plasma is a safe and effective way to treat hair loss.
research Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome.
Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.
research Permeant lipophilicity and vehicle composition influence accumulation of dyes in hair follicles of human skin
Lipophilic dyes accumulate more in hair follicles when delivered with surfactant-propylene glycol solutions.
research Formulation and in vitro evaluation of polymeric enteric nanoparticles as dermal carriers with pH-dependent targeting potential
Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
research Dermal nanocrystals from medium soluble actives – Physical stability and stability affecting parameters
Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
research The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin
Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.
research The investigation of insulin resistance and metabolic syndrome in male patients with early-onset androgenetic alopecia
Early balding men may have insulin resistance, but lifestyle changes can help.
research Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro
Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.
research Reversible alopecia universalis secondary to PEG-interferon ??-2b and ribavirin combination therapy in a patient with chronic hepatitis C virus infection
A woman's total hair loss from hepatitis C treatment grew back after stopping the medication.
research Prevalence and accurate diagnosis of polycystic ovary syndrome in adolescents across world regions: a systematic review and meta-analysis
PCOS affects about 6.3% of teens globally, and ongoing checks are advised for those with irregular cycles or high androgen levels.
research Melatonin vitamin C-based nanovesicles for treatment of androgenic alopecia: Design, characterization and clinical appraisal
Melatonin vitamin C-based nanovesicles improved hair growth and reduced hair loss in androgenic alopecia patients.
research THERAPY OF ENDOCRINE DISEASE: Treatment of hirsutism in the polycystic ovary syndrome
Effective hirsutism treatment for women with PCOS should be personalized and may include lifestyle changes and medication.
research The efficacy of laser-assisted hair removal in the treatment of acne keloidalis nuchae; a pilot study
Laser hair removal significantly improves acne keloidalis nuchae, especially with early treatment.
research Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome.
Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
research Influence of massage and occlusion on the ex vivo skin penetration of rigid liposomes and invasomes
Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
research Non polycystic ovary syndrome–related endocrine disorders associated with hirsutism
Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.