276 citations
,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
89 citations
,
August 2008 in “Human genetics” The EDAR gene greatly affects hair thickness in Asian populations.
87 citations
,
May 2018 in “Scientific Reports” Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
77 citations
,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
58 citations
,
December 2020 in “Mayo Clinic Proceedings” The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
29 citations
,
October 2011 in “British Journal of Dermatology” Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
27 citations
,
April 2018 in “Scientific Reports” Psoriasis patients' immune response to a hair protein depends on their specific gene type.
23 citations
,
March 2009 in “Skin Pharmacology and Physiology” Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.
18 citations
,
January 2016 in “Skin appendage disorders” The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
15 citations
,
May 2021 in “British journal of dermatology/British journal of dermatology, Supplement” Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
14 citations
,
April 2000 in “Animal Science/Animal science” Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
10 citations
,
June 2017 in “Experimental Dermatology” New hair loss treatments have evolved from understanding hair biology and patient needs.
10 citations
,
January 2003 in “Seminars in reproductive medicine” The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
5 citations
,
September 2022 in “Molecular pharmacology” KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.
5 citations
,
June 2015 in “Journal of Investigative Dermatology” Feathers are useful for researching growth, regeneration, and the effects of treatments like chemotherapy on hair loss.
3 citations
,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
2 citations
,
June 2003 in “International Journal of Acarology” Researchers found a new mite species causing severe hair loss and skin problems in yellow-bellied marmots.
1 citations
,
January 2023 in “Frontiers in veterinary science” Activating autophagy in dogs with certain diseases improves their skin and hair.
Finding functions for unknown GPCRs is hard but key for making new drugs.
April 2026 in “npj Regenerative Medicine” Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
The skin can still regenerate and function well even with fewer fibroblasts.
July 2025 in “Indian Journal of Forensic Medicine & Toxicology” DNA phenotyping can predict physical traits like eye, hair, and skin color, improving forensic investigations.
January 2024 in “Bright Sky Publications eBooks” Helicobacter pylori infection is common in Southern Iraq gastritis patients, affecting 64.1%.
January 2017 in “Postepy Dermatologii I Alergologii” The CRH/CRH-R1 system might be involved in causing lichen planus.
July 1997 in “Journal of Cutaneous Medicine and Surgery” Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.
31 citations
,
March 2020 in “International Journal of Regenerative Medicine” PRP treatment can safely boost hormone levels in some IVF patients with low ovarian reserve.