102 citations
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August 2008 in “Genes & Development” Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
98 citations
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November 2002 in “Contact Dermatitis” Many people had severe allergic reactions to a common hair dye ingredient, causing them to seek medical care and miss work.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
93 citations
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June 2001 in “The Journal of Clinical Endocrinology and Metabolism” Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
87 citations
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March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
86 citations
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
81 citations
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June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
81 citations
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December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
80 citations
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June 2000 in “Modern Pathology” Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.
75 citations
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January 1995 in “American journal of primatology” Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.
74 citations
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October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
72 citations
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January 2003 in “American Journal of Pathology” A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
71 citations
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June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
67 citations
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January 2012 in “Biological and Pharmaceutical Bulletin” Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
66 citations
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June 2018 in “International Journal of Women's Dermatology” No cure for female pattern hair loss, but various effective treatments exist.
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April 1995 in “The journal of cell biology/The Journal of cell biology” A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
63 citations
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March 1998 in “Archives of Dermatology” Antidepressants may improve or resolve scalp dysesthesia in most patients.
63 citations
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January 1992 in “Experimental Neurology” Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.
61 citations
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June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
60 citations
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October 2010 in “Molecular Imaging and Biology” Increased skin pigmentation in mice reduces bioluminescent signal accuracy.
59 citations
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December 2016 in “Supportive Care in Cancer” Core symptoms in breast cancer chemotherapy remain stable, aiding targeted interventions.
57 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
57 citations
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June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
55 citations
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May 2017 in “Current stem cell research & therapy” Using fat-derived stem cells for hair loss treatment is safe and effective, improving hair growth and patient satisfaction.
55 citations
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January 2016 in “Annals of Dermatology” Microneedle stimulation can increase hair growth in mice.
55 citations
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August 2015 in “AAPS PharmSciTech” The cream with orange peel and liquorice extracts may help reduce skin aging.
54 citations
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November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
54 citations
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October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.