39 citations
,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
36 citations
,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
36 citations
,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
35 citations
,
January 2014 in “BioMed Research International” Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.
35 citations
,
October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.
35 citations
,
December 2009 in “Human reproduction” Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
34 citations
,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
30 citations
,
December 2001 in “Journal of The European Academy of Dermatology and Venereology” Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
29 citations
,
February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
28 citations
,
July 2022 in “Endocrine” Low prolactin in young women may increase heart and metabolism risks.
27 citations
,
June 2017 in “International Journal of Dermatology” The study suggests that acne keloidalis nuchae is linked to conditions like pseudofolliculitis barbae, scalp infections, metabolic syndrome, and is more common in males with an average onset age of 25.4 years.
26 citations
,
October 2016 in “Clinics in Dermatology” Hormonal treatments can improve acne, but they come with potential side effects and risks.
24 citations
,
March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
23 citations
,
February 2021 in “Journal of Endocrinological Investigation” Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
21 citations
,
July 2014 in “Clinics in Dermatology” Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
20 citations
,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
19 citations
,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
18 citations
,
April 2016 in “Endocrinology and Metabolism Clinics of North America” The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
18 citations
,
May 1992 in “American Journal of Biological Anthropology” Higher androgen levels do not cause baldness in men.
16 citations
,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
15 citations
,
January 1988 in “Drugs” The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
14 citations
,
March 2010 in “Gynecological endocrinology” New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
14 citations
,
January 1980 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Both treatments reduced androgen levels and hair growth in women with hirsutism.
13 citations
,
March 2019 in “Physiological Research” Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.
12 citations
,
March 2018 in “Medicine” A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
11 citations
,
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
11 citations
,
August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
10 citations
,
January 2003 in “Seminars in reproductive medicine” The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
9 citations
,
November 2018 in “Acta Clinica Belgica” Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
9 citations
,
January 2018 in “Journal of the European Academy of Dermatology and Venereology” A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.