January 2006 in “Chinese Journal of Aesthetic Medicine” Zinc improves skin flap survival in rats.
15 citations
,
December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
April 2016 in “Journal of Investigative Dermatology” The Engrailed-1 gene plays a key role in the development of sweat glands in mice.
13 citations
,
August 1999 in “Journal of Investigative Dermatology” Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MOF controls skin development by regulating genes for mitochondria and cilia.
April 2018 in “Journal of Investigative Dermatology” Ceramide synthase 4 is essential for maintaining skin barrier health.
13 citations
,
January 2018 in “Advances in experimental medicine and biology” 38 citations
,
December 2006 in “Journal of Investigative Dermatology” Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.
130 citations
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April 2001 in “Journal of Investigative Dermatology” The keratin tail is crucial for skin structure and function.
May 2024 in “Journal of drug delivery science and technology” Exosomes show promise for treating skin diseases and improving skin regeneration.
46 citations
,
March 2005 in “Endocrinology” Overexpression of the glucocorticoid receptor in mice causes developmental defects similar to ectodermal dysplasia.
49 citations
,
August 1999 in “Journal of Investigative Dermatology” Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
35 citations
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September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.
86 citations
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April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
14 citations
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May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
28 citations
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February 2014 in “PLoS ONE” Epidermal stem cells on a special membrane helped mice regrow full skin with hair and functions.
48 citations
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January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.
10 citations
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June 2022 in “Development” Gene regulation evolved differently in mouse and chicken skin, but remained stable in their trunks.
February 2025 in “Journal of Investigative Dermatology” The ZIP13 variant is linked to abnormal hair quality.
5 citations
,
July 1999 in “Journal of Anatomy” Methylene blue staining effectively reveals detailed nerve structures in rat snouts.
318 citations
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October 1998 in “The Journal of Cell Biology” Keratin 17 is important for skin development and may help define skin cell types.
1 citations
,
July 2025 in “JCI Insight” Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
1 citations
,
February 1991 in “Journal of Biological Chemistry” 33 citations
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February 2012 in “British Journal of Dermatology” Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
2 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.
23 citations
,
August 2017 in “Genome” Gene expression affects fur development in rex rabbits.
9 citations
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July 1961 in “Journal of Investigative Dermatology” Cutaneous calcinosis can be induced in young animals using certain compounds, but only in specific areas and with high mortality.
1 citations
,
April 2012 in “Cancer Research” Antizyme reduces tumor growth and normalizes skin cell development affected by MEK.
April 2017 in “Journal of Investigative Dermatology” The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
Recognizing mild or atypical cases of ectodermal dysplasia is crucial for better treatment and future planning.