February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” A new hair dye method uses polyphenols and oxidation to create a long-lasting brown color on gray hair.
5 citations
,
January 2011 in “International Journal of Cosmetic Science” 1,2,3,4-tetrahydroquinoline compounds are great for stable, pure blue hair dye.
6 citations
,
September 2010 in “Pigment Cell & Melanoma Research” We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.
56 citations
,
January 1996 in “Journal of Forensic Sciences” Dye enters hair at the edges of cuticle cells and penetrates more from water than alcohol-based solutions.
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
January 2006 in “Carl von Ossiezky University of Oldenburg” Unpigmented keratinocytes absorb substances faster, while melanocytes bind more strongly to melanin.
43 citations
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October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
18 citations
,
March 2009 in “Skin pharmacology and physiology” Sunlight damages hair, causing cuticle loss, protein changes, and discoloration.
27 citations
,
January 1995 Melanin in black hair protects it from sun damage better than light-brown hair.
April 2026 in “The FASEB Journal” Exosomal miR-199a-3p from dermal papilla cells helps control hair color by affecting melanocytes.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
1 citations
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November 2004 in “International Journal of Cosmetic Science” External agents penetrate skin more easily in areas with fewer lipids, especially through hair follicles.
35 citations
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March 2007 in “Skin Research and Technology” The conclusion is that exogen is a unique hair cycle phase and the new sampling method specifically targets this stage, which may help in future hair loss research.
10 citations
,
September 2022 in “Journal of Biophotonics” Blue light therapy is safe for skin and may protect against UV radiation.
20 citations
,
February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
November 2021 in “Natural product research” Certain polyphenols may help treat skin pigmentation disorders.
27 citations
,
August 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
1 citations
,
January 2010 in “Biophysical journal” Hair fluorescence intensity can measure radiation exposure effectively.
January 2021 in “Journal of clinical and cosmetic dermatology” Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
July 2025 in “Advanced Science” Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
July 1989 in “British Journal of Dermatology” Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.
22 citations
,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
40 citations
,
October 2009 in “Journal of Biomedical Nanotechnology” Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
April 2026 in “Journal of Cosmetic Dermatology” Exosomes from umbilical cord stem cells help protect hair color and health under stress.
April 2019 in “Journal of Investigative Dermatology” The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
December 2023 in “Modern engineering and innovative technologies” ChromaLens offers more precise and stable hair coloring than traditional methods.