research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
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research CONTRACEPTION AND THE SKIN
Birth control pills can cause skin issues but may help with acne and hirsutism, and choosing the right type can minimize side effects.
research Use of oral contraceptives in the management of acne
Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.
research Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework
A new method effectively predicts estrogen-related health effects for early screening.
research EFFECTS OF HORMONAL THERAPY IN TRANSGENDERS
Hormonal therapy for transgender individuals carries health risks but is a personal choice.
research Hormonal Regulation and Systemic Signals of Skin Aging
Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research Cancer risk in polycystic ovary syndrome patients: Common treatments and future perspectives
PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
research COVID-19 and Sex Differences
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents
Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
research The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta?
Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
research Sex Steroid Hormone Receptors in Human Skin Appendage and its Neoplasms
Sex steroids influence skin appendage function and neoplasm development, with changes in AR and ERalpha in certain gland neoplasms.
research Sex Hormone-Binding Globulin (SHBG) as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome
SHBG may be a useful early indicator and treatment target for PCOS.
research Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Gonadal dysgenesis and bone metabolism
Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
research Metformin influence on hormone levels at birth, in PCOS mothers and their newborns
Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research 5α-Reductase isozymes and aromatase mRNA levels in plucked hair from young women with female pattern hair loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research Getting under the skin of hair aging: the impact of the hair follicle environment
Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
research Medical Treatment of Hirsutism in Women
Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.
research Antiandrogenic activities ofGlycyrrhiza glabrain male rats
Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Endocrine treatment of benign prostatichypertrophy: Current concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Recommendations of endocrine treatment for patients with gender dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
research Preponderance of serum and intra-hepatic 5α-dihydrotestosterone in males with hepatocellular carcinoma despite low circulating androgen levels
Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results
5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach
Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.