49 citations
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February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
45 citations
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June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
44 citations
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September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
41 citations
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December 2008 in “Current Opinion in Ophthalmology” Certain eye surgery complications can be managed effectively, especially in patients who have used specific prostate medications.
39 citations
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December 2012 in “The American Journal of Human Genetics” Mutations in the SNRPE gene cause hereditary hair loss.
31 citations
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August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
30 citations
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December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
27 citations
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July 2013 in “Journal of Investigative Dermatology” Revertant cell therapy shows promise for treating type XVII collagen deficiency, but better cell selection methods are needed.
26 citations
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July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
26 citations
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October 2012 in “Dermatologic Clinics” The document details hair transplantation techniques and innovations, highlighting Follicular Unit Transplantation as the standard and discussing the effectiveness and challenges of the procedure.
26 citations
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January 1992 in “Carcinogenesis” TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
24 citations
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November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
24 citations
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July 2022 in “Journal of Applied Pharmaceutical Science” Optimizing production conditions can improve hyaluronic acid's effectiveness and cost in cosmetics and therapy.
24 citations
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July 2015 in “Molecular Medicine Reports” Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.
23 citations
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May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
22 citations
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September 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
21 citations
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January 2018 in “PLoS Genetics” Certain genetic variants in keratins increase the risk of tooth decay.
21 citations
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April 2014 in “PLoS ONE” A rare gene variant causes hair and nail issues in a family.
21 citations
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September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
20 citations
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October 2023 in “Small” Microneedles show promise for treating hair loss, eye, and mouth diseases.
19 citations
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October 2016 in “Journal of oncology pharmacy practice” A cancer patient's hair became permanently curly after treatment with nivolumab.
18 citations
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January 2023 in “Nano Research” Red OLED therapy significantly boosts hair growth.
17 citations
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September 2000 in “Journal of dermatology” A baby with a rare metabolic disorder developed a rash not cured by zinc alone, likely due to both zinc and amino acid deficiencies.
16 citations
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January 1998 in “PubMed” Sun exposure and genetics increase skin cancer risk from precancerous lesions.
15 citations
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December 2016 in “Obstetrics & Gynecology” Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.
15 citations
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February 2009 in “Cell Stem Cell” The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.
14 citations
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September 2024 in “Cosmetics” Exosomes and cell culture-conditioned media improve skin quality and reduce aging signs.
14 citations
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February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
13 citations
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February 2025 in “ChemMedChem” Lipid nanoparticles improve treatment delivery and are key to future therapies, but challenges in manufacturing and safety remain.
13 citations
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May 2017 in “Current Protocols in Stem Cell Biology” A method was developed to isolate and study hair follicle stem cells from mouse skin.