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Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Ets2 gene is crucial for placental development in mice.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human skin can make serotonin and melatonin.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Contaminated water with heavy metals causes serious health issues like kidney and liver problems.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

PGD2 stops hair growth and is higher in bald men with AGA.

Lactate production is important for activating hair growth stem cells.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Fungi-produced compounds can change plant root growth.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.