Search for ezh2 inhibitors in research

Search for New Antineoplastic Agents Based on Structural Modifications of Steroidal 5α-Reductase, 17β-Hydroxysteroid Dehydrogenase, and 17α-Hydroxylase/17,20-Lyase Inhibitors

research Search for New antineoplastic agents based on structural modifications of steroidal 5α-reductase, 17β-hydroxysteroid dehydrogenase, and 17α-hydroxylase/17,20-lyase inhibitors

November 2025 in “Russian Journal of Oncology”

Modifying steroidal inhibitors shows promise for developing new cancer treatments.

research An Open Randomized Comparative Study of an Oral Contraceptive Containing Ethinyl Estradiol and Cyproterone Acetate with and without the GnRH Analogue Goserelin in the Long-Term Treatment of Hirsutism

18 citations , March 2010 in “Gynecologic and obstetric investigation”

The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.

Oral Combination Treatment of Gefitinib and Sasam-Kyeongokgo: Synergistic Effects on the NCI-H520 Tumor Cell Line

research Oral Combination Treatment of Gefitinib (IressaTM) and Sasam-Kyeongokgo: Synergistic Effects on the NCI-H520 Tumor Cell Line

January 2023 in “Applied sciences”

Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.

research Where is the data? Delayed and chronic irAE surveillance and management after cessation of ICIs: expert insights from SITC on survivorship care and the need for long-term data

March 2026 in “Journal for ImmunoTherapy of Cancer”

Long-term data and a team approach are needed to manage chronic side effects from cancer treatments.

research Trichoscopic Findings of Erosive Pustular Dermatosis of the Scalp Associated with Gefitinib

21 citations , June 2017 in “Case Reports in Dermatology”

Reducing gefitinib dosage improved hair loss, but scarring remained.

research Abstract SS02-02: Chemoprevention: Poised for Success

November 2008 in “Cancer Prevention Research”

Chemoprevention can significantly lower cancer risks and needs more research and collaboration.

research Dr Reddy's Laboratories has announced the launch of its finasteride and simvastatin tablets,

July 2006 in “Inpharma Weekly”

research High‐dose mizoribine treatment for adolescents with systemic lupus erythematosus

16 citations , April 2006 in “Pediatrics International”

High-dose mizoribine effectively controls symptoms in adolescents with lupus while reducing steroid use, with manageable side effects.

research Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation

2 citations , January 2023 in “Redox Report”

Estradiol may protect ear cells from hearing loss caused by a chemotherapy drug by activating a protective pathway.

research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines

January 2023 in “IntechOpen eBooks”

The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.

research Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone. Letter.

1 citations , February 2022 in “The Journal of Urology”

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

research Novel inhibitors of 5α-reductase

20 citations , February 2002 in “Expert Opinion on Therapeutic Patents”

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

research Scalp Pustule as a Manifestation of Erlotinib-Induced Skin Toxicity: Report of Two Cases and Literature Review

1 citations , April 2025 in “Clinical Cosmetic and Investigational Dermatology”

Erlotinib can cause scalp pustules and hair loss, needing early treatment with antibiotics and steroids.