research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
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research Mapping of a novel locus for keratosis follicularis squamosa on chromosome 7p14.3–7p12.1
A new gene location for Keratosis follicularis squamosa was found on chromosome 7p14.3-7p12.1.
research A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
research POLYCYSTIC OVARY SYNDROME (PCOS)–AN OVERVIEW
PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Current and Future Medical Treatment of Androgenetic Alopecia
Treatments for hair loss vary, but cell-based options may be the future.
research A review of the treatment of male pattern hair loss
Finasteride and minoxidil work best together for hair loss.
research Hair loss
The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.
research Body dysmorphic concerns, social adaptation, and motivation for psychotherapeutic support in dermatological outpatients
Some skin patients have body image issues linked to social difficulties but want psychological help.
research The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis
BMS-470539 reduces skin fibrosis and inflammation.
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism
Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
research JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
research ELECTRON MICROSCOPE STUDIES OF HAIR AND WOOL
Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
research Oestrogen functions in skin and skin appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research Does a male polycystic ovarian syndrome equivalent exist?
Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
research 12 Treatment of hirsutism with 5α-reductase inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Thyroid diseases and skin autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Immunology of alopecia areata
Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
research The Metabolism and Control Mechanism of Human Hair Follicles
Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Topical Estrogen Therapy for Androgenetic Alopecia in Menopausal Females
Topical estrogen helps hair growth in menopausal women with no major side effects.
research Hormonal therapy in female pattern hair loss
Hormonal therapies help treat female hair loss, but results are slow and vary.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride and Hair Transplantation
Alternative treatments show promise for hair growth beyond traditional methods.
research Testosterone-like immunoreactivity in hair measured in minute sample amounts - a competitive radioimmunoassay with an adequate limit of detection
The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
research Medical treatment regimens of hirsutism
Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.