The combination of high-dose toremifene and capecitabine was effective for advanced recurrent breast cancer.
67 citations
,
January 2007 in “Climacteric” Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.
January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
248 citations
,
December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
68 citations
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November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
65 citations
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January 2011 in “Frontiers in Endocrinology” Neurosteroids show promise for treating epilepsy and more research is needed.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
40 citations
,
December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
34 citations
,
June 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
19 citations
,
May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
12 citations
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June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
10 citations
,
May 2019 in “International Journal of Environmental Research and Public Health” Finasteride may cause kidney damage.
9 citations
,
April 2006 in “American Journal of Pathology” SGK3 is essential for proper hair growth and health.
2 citations
,
July 2020 in “Behavioural Brain Research” Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.
2 citations
,
January 2011 in “Andrologia” Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
January 2020 in “Journal of Pharmacognosy and Phytochemistry” The VCO-based herbal hair tonic is effective, safe for hair loss treatment, and can be mass-produced.
The data suggests that dosing differences can help manage spasticity in patients with upper motor neuron dysfunction.
The man's scalp tightness after hair surgery affects his life and work, and it's unclear if it's due to the surgery or a mental health issue.
Thoracic medial branch block may be a simpler and effective alternative to thoracic vertebroplasty for pain management.
5 citations
,
August 2022 in “Farmatsevtychnyi zhurnal” Common fennel fruits can be effectively used to make medicines for better digestion.
The research developed new fortilin protein constructs for potential heart disease treatments.
A protein-sparing modified fast can help with short-term weight loss if supervised by a doctor.
80 citations
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October 1985 in “American Journal of Public Health” A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.
4 citations
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January 2013 in “Dissolution Technologies” A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
July 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Mealworm farming is a sustainable, low-cost way to produce high-quality protein-rich feed.
March 2023 in “Oxford University Press eBooks”
April 2023 in “Tikrit Journal of Pharmaceutical Sciences” Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.