369 citations
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June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
359 citations
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September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
343 citations
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October 2015 in “Endocrine Practice” The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
320 citations
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December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
284 citations
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February 2008 in “Pediatrics” Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
254 citations
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September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
193 citations
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January 2015 in “International journal of trichology” Dermatologists need to understand hair products to treat hair and scalp issues better.
173 citations
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May 2001 in “Human reproduction update” Oestrogens are key for bone growth during puberty in both boys and girls.
165 citations
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September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
156 citations
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August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
144 citations
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August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
143 citations
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August 1991 in “Endocrinology” Androgens, like testosterone, are crucial for early testicular descent in rats.
138 citations
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
130 citations
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August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
130 citations
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August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
127 citations
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June 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
120 citations
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October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
101 citations
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July 2021 in “Nature Communications” 4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
95 citations
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February 2018 in “Dermatology and Therapy” Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
88 citations
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June 2016 in “Human Reproduction Update” New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
88 citations
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May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
86 citations
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January 2008 in “Journal of nutritional & environmental medicine” Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.
84 citations
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December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
80 citations
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April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
79 citations
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January 2017 in “Dermatology practical & conceptual” Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.
78 citations
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October 2020 in “Experimental Dermatology” Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
77 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
70 citations
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March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.