research Drug Discovery Insights from a Computational QSAR Study on Alpha-Reductase Inhibitors and Layered Double Hydroxides Electrocatalysts
Computational techniques can improve drug development for treating certain conditions.
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210-240 / 1000+ results research FPRL1 Receptor Agonist Peptides Prevent Etoposide-Induced Alopecia in Neonatal Rats
Certain peptides can prevent hair loss in young rats caused by a cancer drug.
research Treatment of erythromelanosis follicularis faciei et colli with a 595‐nm pulsed dye laser
The 595-nm pulsed dye laser effectively reduces symptoms of EFFC with minimal side effects.
research The effect of polyphloretin phosphate, polyoestradiol phosphate, a diphosphonate and a polyphosphate on calcification induced by dihydrotachysterol in skin, aorta and kidney of rats
The diphosphonate was the most effective at preventing calcification in rats.
research In vivo and in silico evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats
Hesperidin protects rat testicles from finasteride damage and improves sperm health.
research Multifunctional Dynamic Cerium-Polypeptide Hydrogel with Antibacterial Antioxidative Antiinflammatory for Multidrug-Resistant Bacterial Infected Wound Healing
The cerium-polypeptide hydrogel effectively heals drug-resistant bacterial wounds by fighting bacteria, reducing inflammation, and promoting tissue repair.
research Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
research Dual inhibitors of urease and carbonic anhydrase-II from Iris species
Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.
research 1465 Optimization/characterization of a Focal Dermal Hypoplasia mouse model to test potential treatments
Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
research LB1077 Cutaneous responses to systemic iron: A potential role for epidermal turnover in mammalian iron excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research Antitumour and toxic effects on Wistar rats of two new platinum complexes
The new platinum complexes effectively increased survival in rats with tumors, despite some reversible side effects.
research Nutritional therapy versus 6-mercaptopurine as maintenance therapy in patients with Crohn's disease
Elental is a good long-term treatment for Crohn's disease, similar to 6-mercaptopurine but with fewer side effects.
research Antagonistic Effect of Iodides in Baldness and Toxicity due to Thallium Acetate
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research Used Right, IV Arsenic Is Safe & Effective
Intravenous arsenic is safe and effective for treating certain blood cancers.
research New fluorogenic probes for neutral and alkaline ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Fluoroquinolone-induced serious, persistent, multisymptom adverse effects
Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
research Effect of FOLFOX6 chemotherapy on serum VEGF expression in advanced colorectal cancer patients
FOLFOX6 chemotherapy effectively reduces VEGF levels and improves quality of life in advanced colorectal cancer patients.
research Introduction to this second series of Biometals webinars, The biology of mammalian multi-copper ferroxidases, Arsenic antibiotics: old and new
Some bacteria use arsenic compounds as antibiotics, and others have evolved resistance; a particular arsenic-based compound shows potential as a new antimalarial treatment.
research Selenium Toxicity: A Case of Selenosis Caused by a Nutritional Supplement
Excessive selenium from supplements can be harmful.
research Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.
TCDD reduces EGF receptor activity and causes various developmental changes in animals.
research Tea Polyphenol–Zinc Nanocomplexes Alleviate Diquat-Induced Liver and Small Intestine Oxidative Stress in C57BL/6 Mice
Tea polyphenol–zinc helps protect the liver and intestines from oxidative stress.
research Case report: Successful treatment of a thallium sulfate intoxication in a dog with use of Prussian blue
Prussian Blue successfully treated thallium poisoning in a dog.
research Injectable self-healing ceria-based nanocomposite hydrogel with ROS-scavenging activity for skin wound repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma
Chemotherapy improved a girl's painful foot condition linked to pachyonychia congenita.
research A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride
Desolvation of finasteride depends on environment and technique.
research Comparison of Efficacy and Specificity in Cancer‐Targeting Prodrug Conjugates
The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.
research Experimental Assessment of 3-meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors in silico and in vivo Models
The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
Researchers developed a less damaging way to extract red dyes from wool using EDTA and DMF, preserving the fiber's strength for further analysis.
research Effect of Various Dietary Factors on the Deposition of Selenium in the Hair and Nails of Rats
Selenium in hair and nails is higher with L-selenomethionine and low methionine.