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Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp

research Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp

14 citations , October 2020 in “Scientific reports”

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men

14 citations , January 2018 in “Advances in Clinical Chemistry”

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Metabolic Syndrome and Insulin Resistance Syndrome Among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam

research Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam

14 citations , January 2018 in “Endocrinology and Metabolism”

Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.

research Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens

14 citations , November 2014 in “European journal of medicinal chemistry”

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

research KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis

13 citations , March 2021 in “British Journal of Pharmacology”

KY19382 helps regrow hair and create new hair follicles.

research Effects of Long Term Treatment With Finasteride (MK-906), a 5-Alpha Reductase Inhibitor, on Circulating LH, FSH, Prolactin and Estradiol

10 citations , October 1992 in “Hormone and Metabolic Research”

Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.

Prostaglandins in Androgenetic Alopecia in 12 Men and Four Women

research Prostaglandins in androgenetic alopecia in 12 men and four female

8 citations , February 2019 in “Journal of The European Academy of Dermatology and Venereology”

research Role of 5α-dihydrotestosterone in testicular development of gilthead seabream following finasteride administration

8 citations , July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology”

DHT affects testicular development and regulates spermatogenesis in some fish.

research Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride

8 citations , February 2014 in “General and Comparative Endocrinology”

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

The Overexpression of R-Spondin 3 Affects Hair Morphogenesis and Development Along with the Formation and Maturation of Hair Follicle Stem Cells

research The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells

6 citations , September 2024 in “Frontiers in Physiology”

Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.

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