Lower DHT and higher testosterone levels increase brain activation but don't change behavior in heavy drinkers.
13 citations
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May 2007 in “Journal of Endocrinology” Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
21 citations
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February 2003 in “Hormones and Behavior” Androgens boost certain nest-building behaviors and greatly reduce food intake in rabbits.
11 citations
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January 2019 in “Sexual Medicine” Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.
April 2023 in “Mayo Clinic Proceedings” Estrogen may help improve COVID-19 outcomes, especially in women.
58 citations
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January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
February 2024 in “The Journal of Sexual Medicine” 5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
25 citations
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July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
25 citations
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June 2017 in “Scientific reports” Stress worsens Tourette symptoms by increasing allopregnanolone levels.
Finasteride and dutasteride can harm male reproductive health, affecting sperm and causing sexual dysfunction.
24 citations
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July 1980 in “Journal of Toxicology and Environmental Health” High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
1 citations
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November 1995 in “Postgraduate medical journal” A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
54 citations
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September 2013 in “Fertility and Sterility” Finasteride can reduce fertility in some men, but stopping it increases sperm count.
17 citations
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January 1995 in “The American Journal of Medicine” The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.
1 citations
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April 2020 in “Medico-Legal Update” The flower extract lowered testosterone, progesterone, and related gene expression in male rats.
4 citations
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January 1991 in “Journal of dermatological treatment” Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.
June 2025 in “Journal of the American Academy of Dermatology” 15 citations
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March 2015 in “PloS one” Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
39 citations
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January 2012 in “Indian Dermatology Online Journal” Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
2 citations
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July 2021 in “The Journal of Sexual Medicine” Gene expression differences in PFS patients suggest a potential organic cause for symptoms.
October 2025 in “Journal of the Endocrine Society” Hormone Replacement Therapy improves skin health in postmenopausal women by boosting collagen and hydration.
1 citations
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July 2025 in “BMC Psychology” Social rejection can harm long-term mental health in transgender individuals.
June 2018 in “Journal of Clinical Periodontology” Finasteride can cause gum swelling and bleeding, but stopping the drug helps recovery.
4 citations
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December 2012 in “Arquivos Brasileiros De Endocrinologia E Metabologia” A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
21 citations
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January 2017 in “Dermatology Online Journal” Finasteride and dutasteride can cause sexual problems like impotence and low libido.
7 citations
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April 2011 in “American journal of obstetrics and gynecology” A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.
April 2017 in “European Psychiatry” Some antidepressants can cause emotional numbness and other unusual side effects.
4 citations
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October 2021 in “Canadian Journal of Physiology and Pharmacology” Women with pancreatic cancer are more likely to have certain side effects from chemotherapy than men.
137 citations
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March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
22 citations
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March 2003 in “Steroids” PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.