research Cutaneous distribution of orally administered itraconazole in guinea pigs, studied by autoradiography
Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.
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570-600 / 1000+ results research Management of pyoderma associated with demodicosis in a dog- A case report
The dog's skin disease was successfully treated with medication and supplements.
research Histological and immunohistochemical examination of the effect of the nonsteroidal antiandrogen {flutamide} on some organs of the male reproductive system in albino rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research SUCCESSFUL MANAGEMENT OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA)-ASSOCIATED PYODERMA IN A DOG
A dog's MRSA skin infection was cured with linezolid and fungal treatment in 28 days.
research Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring
Inhibiting 5α-reductase during late pregnancy shortens gestation, reduces litter size, and harms memory in rat offspring.
research Quality evaluation of the Finasteride polymorphic forms I and II in capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research Early postnatal inhibition of neurosteroid synthesis changes the later-life adverse outcome of neonatal asphyxia in rats
Finasteride reduced seizures and prevented cognitive issues in rats after neonatal asphyxia but increased anxiety later.
research BAYONET trial: staged combination with encorafenib, binimetinib, plus cetuximab following encorafenib plus cetuximab for BRAF V600E-mutant metastatic colorectal cancer
The combination treatment showed a higher response rate but no significant survival benefits.
research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research The efficacy of subcutaneous slow‐release melatonin implants in the prevention of canine flank alopecia recurrence is uncertain: A double‐blind, randomized, placebo‐controlled study
Melatonin implants did not effectively prevent hair loss in dogs.
research Infestation Diagnosis of Ectoparasitism in Red Fox and Jackles in South-west of Iran
About 19% of foxes and 18% of jackals in southwest Iran have at least one type of ectoparasite, mainly fleas.
research Detection of testosterone propionate administration in horse hair samples
Hair analysis can detect testosterone in horses after drug administration.
research Generalized Alopecia with Vasculitis-Like Changes in a Dog with Babesiosis
The dog's skin and anemia issues returned after stopping treatment for Babesia gibsoni.
research Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation
research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
research The 5α-reductase inhibitor finasteride reduces opioid self-administration
Finasteride may help reduce opioid use.
research Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice
Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.
research A 5α-reductase inhibitor, finasteride, increases differentiation and proliferation of embryonal carcinoma cell-derived-neural cells
research The cascading pathogenic consequences of Sarcoptes scabiei infection that manifest in host disease
Sarcoptes scabiei infection causes significant health and behavior changes in wombats.
research Finasteride reduces the preventive effect of uroselective α1A-blockers against cancellous bone disorders induced by androgen deficiency in rats
Finasteride weakens the bone-protective effects of certain blockers in low androgen conditions.
research Tinea Capitis Caused by Microsporum ferrugineum in an Infant during the First Year of Life
Griseofulvin effectively treats tinea capitis in infants.
research Spermatogenic and Androgenic Potential of Nephrolepis biserrata on Testosterone- Propionate Induced Benign Prostatic Hyperplasia In Male Wistar Rats
Nephrolepis biserrata may improve fertility and reduce prostate issues in males.
research Alopecia attributed to neoplastic ovarian tissue in two ferrets.
Hair loss in two ferrets was caused by ovarian tissue tumors, not adrenal issues.
research Alopecia universalis in a dog with testicular neoplasia
A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
research Modulation of AR-FGF-2-TGF beta Axis by Cosmos caudatus Suppresses Prostatic Epithelial Proliferation in a BPH Rat Model: A Comparative Study with Finasteride
Cosmos caudatus extract is as effective as finasteride for treating benign prostatic hyperplasia without its side effects.
research Treatment of tinea capitis – a critical appraisal
Griseofulvin is the best treatment for tinea capitis in children, but more research is needed on other treatments and safety.
research Bicalutamide: A potential new oral antiandrogenic drug for female pattern hair loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size
Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
research Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)
BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
research The Antiepileptic and Antidepressant-Like Effects of Dexpanthenol in Female Swiss Albino Mice
Dexpanthenol may help treat epilepsy and depression.