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June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
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May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
260 citations
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December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
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July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
256 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
253 citations
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March 2006 in “The Journal of Clinical Endocrinology and Metabolism” Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
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February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
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December 2013 in “Scientific Reports” A new method quickly creates controllable cell clusters for tissue engineering and drug testing.
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October 2020 in “Microsystems & Nanoengineering” Microtechnology methods improve organoid production for medical research.
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October 2014 in “Annual Review of Pharmacology and Toxicology” Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
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April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
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November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
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March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
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May 2009 in “Plant physiology” Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.
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December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
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January 2014 in “BioMed Research International” AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.
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July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
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May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
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January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
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September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
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September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
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January 2018 in “Burns & Trauma” Bioprinting could improve wound healing but needs more development to match real skin.
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June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
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August 1991 in “Endocrinology” Androgens, like testosterone, are crucial for early testicular descent in rats.
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December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
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March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.