253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created skin-like structures from stem cells that include features like hair and sweat glands.
1 citations
,
November 2021 in “Revista Científica Hospital Santa Izabel” Adhesion molecules are crucial for fetal hair growth.
74 citations
,
June 2021 in “Frontiers in Cell and Developmental Biology” Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
11 citations
,
January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.
2 citations
,
May 2021 in “Scientific Reports” Stress is likely causing hair loss in Formosan macaques.
8 citations
,
July 2019 in “Cell Proliferation” Researchers found a way to turn skin cells into cells that can grow new hair.
July 2025 in “Journal of Investigative Dermatology” Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
21 citations
,
October 2007 in “Journal of Investigative Dermatology” Fetuin-A helps wounds heal without scars by promoting cell movement.
3 citations
,
August 2023 in “World Journal of Biology and Biotechnology” The human microbiome is vital for health and can help treat diseases.
August 2024 in “Revista Científica Multidisciplinar Núcleo do Conhecimento” Malassezia restricta may be linked to intestinal diseases like Crohn's and ulcerative colitis.
5 citations
,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
87 citations
,
February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
7 citations
,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
322 citations
,
October 2006 in “British Journal of Clinical Pharmacology” Warfarin is effective but risky, requiring careful monitoring to prevent bleeding.
April 2023 in “Journal of Investigative Dermatology” Ectomesenchyme is a key source of skin stem cells.
April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
4 citations
,
December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
142 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
168 citations
,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
January 2021 in “Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)” N-Cadherin is crucial in scar formation, offering potential for scar prevention therapies.
December 2021 in “Morphologia” Neural crest cells could be used in regenerative medicine due to their ability to become different cell types.
36 citations
,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
89 citations
,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
56 citations
,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
2 citations
,
January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
1 citations
,
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.